Receptor complex formation of the receptor-like kinase LORE in innate immunity
M. SCHÄFFER (1), S. Eibel (1), T. Illig (1), L. Raasch (1), R. Hückelhoven (1), S. Ranf (1) (1) TU München, Germany

Plants evolved molecular strategies to struggle against pathogens. Perception of conserved microbe-associated molecular patterns (MAMPs) like lipopolysaccharide (LPS) leads to activation of defence responses in plants. This so-called pattern-triggered immunity (PTI) is mediated by specific pattern recognition receptors (PRRs) at the cell surface. Binding of MAMPs to the respective PRR triggers several downstream responses, for instance calcium signalling and reactive oxygen species production. The signal transduction requires the formation and activation of receptor complexes. Recently, we identified the receptor-like kinase LORE (LipoOligosaccharide-specific Reduced Elicitation) as a key component of LPS signalling in Arabidopsis thaliana. LORE is part of the plant-specific class of bulb-type lectin S-domain-1 kinases (SD-RLKs) with 32 members in Arabidopsis and is related to the self-incompatibility conferring S-locus receptor kinase SRK of Brassica. SRK forms homodimers in a ligand-independent manner. Our findings show that LORE is also able to form homodimers in the absence of LPS. Further work aims to elucidate LORE receptor complex formation and to identify extracellular domains essential for receptor dimerization.

Abstract Number: P17-602
Session Type: Poster